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Levi MM et al. – The mechanism, of this platelet–protective effect has, besides a potential prevention of plasmin–mediated loss of platelet receptors not been elucidated. Whether the pro–hemostatic effect of the anti–fibrinolytic agents will eventually result in a higher incidence of thromboembolic complications is still a matter of debate (see further), however, this has so far not been shown in straightforward clinical trials.

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