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See Latest ArticlesThe contribution of deleterious DPYD gene sequence variants to fluoropyrimidine toxicity in British cancer patients
Cancer Chemotherapy and Pharmacology, 10/07/09
Loganayagam A et al. – Contrary to previous estimates for a UK population, genetic DPD deficiency accounts for around 19% of cases of severe fluoropyrimidine toxicity. The influence of DPD deficiency is such that toxicity can be avoided by prior testing and appropriate 5–FU dose/regimen alteration.
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Today in Basic Science/Genetics...keeping you current
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Target genes suitable for silencing approaches and protein product interference in ovarian epithelial cancer
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Dysregulation of Platelet-Derived Growth Factor beta-Receptor Expression by deltaNp73 in Neuroblastoma
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Today in Pharmacology/Therapy...keeping you current
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Management of patients with advanced bladder cancer following major response to systemic chemotherapy
Expert Review of Anticancer Therapy, 12/04/09
ML17032 trial: capecitabine/cisplatin versus 5-fluorouracil/cisplatin as first-line therapy in advanced gastric cancer
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Degarelix 240/80 mg: a new treatment option for patients with advanced prostate cancer
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Today in Side Effects...keeping you current
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Immunoglobulin G Fc Receptor FcgammaRIIIa 158 V/F Polymorphism Correlates With Rituximab-Induced Neutropenia After Autologous Transplantation in Patients With Non-Hodgkin's Lymphoma
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Hepatic Toxicities Associated with the Use of Preoperative Systemic Therapy in Patients with Metastatic Colorectal Adenocarcinoma to the Liver
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