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Molecular characterization of a novel mutation in the factor XIII a subunit gene associated with a severe defect: importance of prophylactic substitution
Blood Coagulation & Fibrinolysis, 10/07/09
Morange P et al. – Mutation gene analysis found a homozygous four bases insertion predicting a stop codon seven residues after PRO675. Antigen assay indicated that the mutant molecule is secreted. This case highlights the importance of prophylactic FXIII infusion.
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Today in Basic Science/Genetics...keeping you current
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