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See Latest ArticlesComparative Analyses of Chromosome Alterations in Soft-Tissue Metastases within and across Patients with Castration-Resistant Prostate Cancer
Cancer Research, 10/06/09
Holcomb IN et al. – Androgen deprivation is the mainstay of therapy for progressive prostate cancer. Despite initial and dramatic tumor inhibition, most men eventually fail therapy and die of metastatic castration–resistant (CR) disease. The authors find the fusion in 54% of the CR tumors, and 81% of the fusion–positive tumors contain cells with multiple copies of the fusion. The investigation lays the foundation for a better understanding of and possible therapeutic targets for CR disease, the poorly responsive and final stage of prostate cancer.
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Today in Basic Science/Genetics...keeping you current
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Target genes suitable for silencing approaches and protein product interference in ovarian epithelial cancer
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Dysregulation of Platelet-Derived Growth Factor beta-Receptor Expression by deltaNp73 in Neuroblastoma
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Today in Renal/Urologic...keeping you current
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Management of patients with advanced bladder cancer following major response to systemic chemotherapy
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