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The Insulin-like Growth Factor-1 Receptor–Targeting Antibody, CP-751,871, Suppresses Tumor-Derived VEGF and Synergizes with Rapamycin in Models of Childhood Sarcoma
Cancer Research, 10/05/09
Kurmasheva RT et al. – These data suggest a model in which blockade of IGF–1R suppresses tumor–derived VEGF to a level where rapamycin can effectively suppress the response in vascular endothelial cells.
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Today in Basic Science/Genetics...keeping you current
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Knockdown of peroxisome proliferator-activated receptor-beta induces less differentiation and enhances cell–fibronectin adhesion of colon cancer cells
Oncogene, 11/25/09
A novel translational approach for human malignant pleural mesothelioma: heparanase-assisted dual virotherapy
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Embryoid body formation of human amniotic fluid stem cells depends on mTOR
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Today in Pediatric Heme/Oncology...keeping you current
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Peripheral arterial tonometry in assessing endothelial dysfunction in pediatric sickle cell disease
Pediatric Hematology and Oncology, 11/25/09
Hepatoblastoma metastatic to the right atrium responding to chemotherapy alone
Pediatric Hematology and Oncology, 11/25/09
Association between defb1 gene haplotype and herpes viruses seroprevalence in children with acute lymphoblastic leukemia
Pediatric Hematology and Oncology, 11/25/09
Today in Soft Tissue/Sarcoma...keeping you current
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Consolidation with high-dose chemotherapy and stem cell support for responding patients with metastatic soft tissue sarcomas: prospective, single-institutional phase II study
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The value of local treatment in patients with primary, disseminated, multifocal Ewing sarcoma (PDMES)
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