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Micallef J et al. – Elucidation of mechanisms that promote EGFRvIII–mediated tumorigenesis in GBM, such as MARCKS, provides additional understanding and potential biological targets against this currently terminal human cancer.

Exclusive Author Commentary
Abhijit Guha, 10/14/09

This article demonstrates the multi-disciplinary approach required towards our understanding of the molecular basis of human diseases such as malignant gliomas. Being able to elucidate the various molecular profiles that contribute towards the aggressiveness of gliomas will help direct patient specific therapy.

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