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Epidermal Growth Factor Receptor Variant III–Induced Glioma Invasion Is Mediated through Myristoylated Alanine-Rich Protein Kinase C Substrate Overexpression
Cancer Research, 10/05/09
Micallef J et al. – Elucidation of mechanisms that promote EGFRvIII–mediated tumorigenesis in GBM, such as MARCKS, provides additional understanding and potential biological targets against this currently terminal human cancer.
Abhijit Guha, 10/14/09
| This article demonstrates the multi-disciplinary approach required towards our understanding of the molecular basis of human diseases such as malignant gliomas. Being able to elucidate the various molecular profiles that contribute towards the aggressiveness of gliomas will help direct patient specific therapy. |
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Today in Basic Science/Genetics...keeping you current
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Association between global DNA hypomethylation in leukocytes and risk of breast cancer
Carcinogenesis, 11/30/09
The Rac1/MKK7/JNK pathway signals upregulation of Atg5 and subsequent autophagic cell death in response to oncogenic Ras
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The extracellular loop 2 of TM4SF5 inhibits integrin alpha2 on hepatocytes under collagen type I environment
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Today in Neurologic Oncology...keeping you current
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Quantitative F18-fluorodeoxyglucose positron emission tomography accurately characterizes peripheral nerve sheath tumors as malignant or benign
Cancer, 11/30/09
Radiosurgery and whole brain therapy in the treatment of brainstem metastases
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