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The effects of BAFF and BAFF-R-Fc fusion protein in immune thrombocytopenia
Blood, 10/02/09
Zhu X–J et al. – BAFF may play a pathogenic role in ITP by promoting the survival of CD19+ and CD8+ cells, increasing the apoptosis of platelets and the secretion of IFN–gamma. Blockade of BAFF by BR3–Fc might be a promising therapeutic approach for ITP.
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