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PAUF functions in the metastasis of human pancreatic cancer cells and upregulates CXCR4 expression
Oncogene, 10/01/09
Lee Y et al. – Immunohistochemical analysis of pancreatic tumor tissues clearly showed a significant positive correlation between PAUF and CXCR4 expression. Collectively, these findings indicate that PAUF enhances the metastatic potential of pancreatic cancer cells, at least in part, by upregulating CXCR4 expression.
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