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Synergistic efficacy of sorafenib and genistein in growth inhibition by down regulating angiogenic and survival factors and increasing apoptosis through upregulation of p53 and p21 in malignant neuroblastoma cells having N-Myc amplification or non-amplification
Investigational New Drugs, 10/08/09
Choudhury SR et al. – Combination of SF and GST inhibited angiogenic and survival factors and increased apoptosis via receptor and mitochondria mediated pathways in both neuroblastoma SK–N–DZ and SH–SY5Y cell lines. Thus, this combination of drugs could be a potential therapeutic strategy against human malignant neuroblastoma cells having N–Myc amplification or non–amplification.
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Activating Peroxisome Proliferator-Activated Receptor gamma Mutant Promotes Tumor Growth In vivo by Enhancing Angiogenesis
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Today in Pharmacology/Therapy...keeping you current
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Efficacy of escalated imatinib combined with cytarabine in newly diagnosed patients with chronic myeloid leukemia
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