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See Latest ArticlesThe oncogenic roles of Notch1 in astrocytic gliomas in vitro and in vivo
Journal of Neuro-Oncology, 10/01/09
Xu P et al. – Knockdown of Notch1 expression by siRNA simultaneously downregulated the expression of EGFR and the important components of its downstream pathways, including PI3K, p–AKT, K–Ras, cyclin D1 and MMP9, indicating the crosstalk and interaction of Notch and EGFR signaling pathways.
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Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination
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Today in Basic Science/Genetics...keeping you current
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HER2 overexpression and amplification is present in a subset of ovarian mucinous carcinomas and can be targeted with trastuzumab therapy
BMC Cancer, 12/20/09
Telomere shortening and chromosomal instability in myelodysplastic syndromes
Genes, Chromosomes and Cancer, 12/20/09
The mitogen-activated protein kinase signaling pathways: role in megakaryocyte differentiation
Journal of Thrombosis and Haemostasis, 12/20/09
Today in Neurologic Oncology...keeping you current
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EZH2 Is Essential for Glioblastoma Cancer Stem Cell Maintenance
Cancer Research, 12/20/09
Acyl-CoA Synthetase VL3 Knockdown Inhibits Human Glioma Cell Proliferation and Tumorigenicity
Cancer Research, 12/20/09
Mutant Metabolic Enzymes Are at the Origin of Gliomas
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