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See Latest ArticlesIdentification of a VWF peptide antagonist that blocks platelet adhesion under high shear conditions by selectively inhibiting the VWF-collagen interaction
Journal of Thrombosis and Haemostasis, 09/25/09
Szanto T et al. – First peptide antagonist has been identified that binds to the VWF C domain and by this specifically inhibits the VWF binding to collagen, suppressing platelet adhesion and aggregation under high shear conditions. As a consequence, this peptide and its future derivates are potentially interesting antithrombotic agents.
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