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Lorusso D et al. – The aim of this article is to review the role of topotecan (Hycamtin), a semi–synthetic alkaloid derivative of camptothecin, in ovarian and cervical cancer in monotherapy and in combination. Topotecan (Hycamtin) will continue to play a role in the treatment of advanced ovarian and cervical cancer, in monotherapy or in combination with other cytotoxic agents.


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