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5-azacitidine prolongs overall survival in patients with myelodysplastic syndrome - systematic review and meta-analysis
Haematologica, 09/25/09
Gurion R et al. – Since 5–azacitidine prolongs overall survival and time to transformation or death it should be highly considered in the treatment of high risk MDS patients. Further studies are needed to establish the exact role of decitabine compared to 5–azacitidine in these patients.
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Today in Leukemia/Lymphoma...keeping you current
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Routine use of ancillary investigations in staging diffuse large B-cell lymphoma improves the International Prognostic Index (IPI)
Journal of Hematology & Oncology, 11/25/09
Association between defb1 gene haplotype and herpes viruses seroprevalence in children with acute lymphoblastic leukemia
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Immunochemotherapy and autologous stem-cell transplantation for untreated patients with mantle-cell lymphoma: CALGB 59909
Journal of Clinical Oncology, 11/25/09
Today in Myeloproliferative Dz...keeping you current
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Sorafenib, a dual Raf kinase/vascular endothelial growth factor receptor inhibitor has significant anti-myeloma activity and synergizes with common anti-myeloma drugs
Oncogene, 11/25/09
International Prognostic Scoring System-independent cytogenetic risk categorization in primary myelofibrosis
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Polycythemia vera erythroid precursors exhibit increased proliferation and apoptosis resistance associated with abnormal RAS and PI3K pathway activation
Experimental Hematology, 11/25/09
Today in Pharmacology/Therapy...keeping you current
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Sorafenib, a dual Raf kinase/vascular endothelial growth factor receptor inhibitor has significant anti-myeloma activity and synergizes with common anti-myeloma drugs
Oncogene, 11/25/09
Pharmacogenetics of telatinib, a VEGFR-2 and VEGFR-3 tyrosine kinase inhibitor, used in patients with solid tumors
Investigational New Drugs, 11/25/09
Adding more content to screening: reactivation of FOXO as a therapeutic strategy
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