Oncology Medical News about Histiocytosis Histiocytosis, Langerhans-Cell

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Improved outcome of refractory Langerhans cell histiocytosis in children with hematopoietic stem cell transplantation in Japan
Bone Marrow Transplantation, 09/23/09

Kudo K et al. – Langerhans cell histiocytosis (LCH) that is refractory to conventional chemotherapy has a poor outcome. Hematopoietic stem cell transplanta tion (SCT) is a promising approach for refractory LCH because of its immunomodulatory effect. The results indicate that SCT is promising as a salvage approach for children with refractory LCH.

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MACOP-B regimen in the treatment of adult Langerhans cell histiocytosis: experience on seven patients
Annals of Oncology, 10/30/09 Relevance Score: 80%

Macrophages in Langerhans cell histiocytosis are differentiated toward M2 phenotype: Their possible involvement in pathological processes
Pathology International, 11/19/09 Relevance Score: 79%

High incidence of hearing loss in long-term survivors of multisystem langerhans cell histiocytosis
Pediatric Blood & Cancer, 10/22/09 Relevance Score: 79%

Neurodegenerative central nervous system Langerhans cell histiocytosis and coincident hydrocephalus treated with vincristine/cytosine arabinoside
Pediatric Blood & Cancer, 11/18/09 Relevance Score: 78%

CD30 positive anaplastic large-cell lymphoma mimicking Langerhans cell histiocytosis
Journal of Cutaneous Pathology, 10/12/09 Relevance Score: 78%