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See Latest Articles'Loss of pigment epithelium-derived factor enables migration, invasion and metastatic spread of human melanoma'
Oncogene, 09/24/09
Orgaz JL et al. – The results show that loss of PEDF enables melanoma cells to acquire an invasive phenotype and, therefore, modulation of this multifunctional factor could be critical for the malignant progression of human melanoma.
B Jimenez, 10/02/09
| Pigment epithelium-derived factor (PEDF) is a multifunctional secreted glycoprotein that displays broad anti-tumor activity based on dual targeting of the tumor microenvironment (anti-angiogenic action) and the tumor cells (direct anti-tumor action). Our results demonstrate that loss of PEDF enables melanoma cells to acquire an invasive phenotype and therefore, modulation of this multifunctional factor could be critical for the malignant progression of human melanoma. |
Today in Basic Science/Genetics...keeping you current
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Efficacy of plasma vascular endothelial growth factor in monitoring first-line chemotherapy in patients with advanced non-small cell lung cancer
BMC Cancer, 12/06/09
SULT1A1 R213H polymorphism and breast cancer risk: A meta-analysis based on 8,454 cases and 11,800 controls
Breast Cancer Research and Treatment, 12/06/09
Applicability of IG/TCR gene rearrangements as targets for minimal residual disease assessment in a population-based cohort of Swedish childhood acute lymphoblastic leukaemia diagnosed 2002-2006
European Journal of Haematology, 12/06/09
Today in Dermatologic Oncology...keeping you current
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JWA regulates melanoma metastasis by integrin alphaVbeta3 signaling
Oncogene, 12/04/09
Immunocryosurgery for basal cell carcinoma: results of a pilot, prospective, open-label study of cryosurgery during continued imiquimod application
Journal of the European Academy of Dermatology and Venereology, 12/02/09
Self-reported screening for skin cancer in Austria
European Journal of Dermatology, 12/02/09
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