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See Latest ArticlesLoss-of-function genetic screens as a tool to improve the diagnosis and treatment of cancer
Oncogene, 09/24/09
Mullenders J et al. – A major impediment to the effective treatment of cancer is the molecular heterogeneity of the disease, which is also reflected in an equally diverse pattern of clinical responses to therapy. In this study, the authors discuss how RNA interference–based genetic screens can be used to address these two pressing needs in the care for cancer patients.
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Immunoprofile of mesenchymal chondrosarcoma: aberrant desmin and EMA expression, retention of INI1, and negative estrogen receptor in 22 female-predominant central nervous system and musculoskeletal cases
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