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See Latest ArticlesCo-expression of survivin, c-erbB2, and cyclooxygenase-2 (COX-2): prognostic value and survival of endometrial cancer patients
Journal of Cancer Research & Clinical Oncology, 09/28/09
Lambropoulou M et al. – These results indicate that the co-expression score has independent prognostic value for endometrial cancer.
Methods- 110 patients with primary untreated endometrial carcinomas
- Tumor tissue biopsies studied by immunohistochemistry
- Statistical analysis evaluated correlation of antigen expression with tumor stage, grade, myometrial invasion, and histologic type
- Association with disease outcome was also investigated
- Expression of 3 antigens independently associated with histological grade, disease stage, and myometrial invasion
- Clinicopathological parameters also associated with number of antigens expressed by each tumor, the expression of more antigens correlating with advanced stage disease and deep myometrial invasion
- In 10-year follow-up, patients with tumors expressing more of these 3 antigens had significantly lower survival rate that with smaller expression score
Today in Basic Science/Genetics...keeping you current
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Prostate cancer stromal cells and LNCaP cells coordinately activate the androgen receptor through synthesis of testosterone and dihydrotestosterone from dehydroepiandrosterone
Endocrine-Related Cancer, 12/09/09
A risk stratification by hormonal receptors (ER, PgR) and HER-2 status in small (≤ 1 cm) invasive breast cancer: Who might be possible candidates for adjuvant treatment?
Breast Cancer Research and Treatment, 12/09/09
Comprehensive characterization of the DNA amplification at 13q34 in human breast cancer reveals TFDP1 and CUL4A as likely candidate target genes
Breast Cancer Research, 12/09/09
Today in Gynecologic Oncology...keeping you current
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Prognostic significance of Dicer expression in ovarian cancer - link to global microRNA changes and oestrogen receptor expression
The Journal of Pathology, 12/09/09
Diet and predictors of dietary intakes in women with family history of breast and/or ovarian cancer
Cancer Epidemiology, 12/09/09
Association between cervical dysplasia and human papillomavirus in HIV seropositive women from Johannesburg South Africa
Cancer Causes and Control, 12/09/09
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