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Sasaki Y et al. – rHuEpo beta does not stimulate tumour growth of the investigated cell line through a direct interaction with tumour cells. Interactions with stromal cells and the stimulation of wound healing responses might, at least partly, explain the negative effects of ESA administration during cancer treatment. EpoR expression in HNSCC tumour cells might not be a good marker for prediction of ESA induced worsening of outcomes after cancer treatment.



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