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Preclinical activity of gefitinib in non-keratinizing nasopharyngeal carcinoma cell lines and biomarkers of response
Investigational New Drugs, 10/08/09
Ma BBY et al. – This study suggests that most NPC cell lines are intrinsically resistant to gefitinib (except HK1 cells), and further studies are needed to confirm whether EGFR gene amplification and persistent AKT activation may influence response to gefitinib in NPC.
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Today in Basic Science/Genetics...keeping you current
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HER2/neu expression correlates with vascular endothelial growth factor-C and lymphangiogenesis in lymph node-positive breast cancer
Annals of Oncology, 12/01/09
Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states
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In situ cytotoxic and memory T cells predict outcome in patients with early-stage colorectal cancer
Journal of Clinical Oncology, 11/30/09
Today in Head and Neck...keeping you current
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Survey on human papillomavirus/p16 screening use in oropharyngeal carcinoma patients in the United States
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Cytological features of cystadenocarcinoma in cyst fluid of the parotid gland: Diagnostic pitfalls and literature review
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Guggulsterone enhances head and neck cancer therapies via inhibition of signal transducer and activator of transcription-3
Carcinogenesis, 11/30/09
Today in Pharmacology/Therapy...keeping you current
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Phase II study of carboplatin combined with weekly docetaxel in patients with advanced non-small cell lung cancer
Cancer Chemotherapy and Pharmacology, 12/01/09
Results of a phase II study of bortezomib in patients with relapsed or refractory indolent lymphoma
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Treatment of recurrent platinum-resistant ovarian cancer with pegylated liposomal doxorubicin ; An evaluation of the therapeutic index with special emphasis on cardiac toxicity
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