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Lovastatin overcomes gefitinib resistance in human non-small cell lung cancer cells with K-Ras mutations
Investigational New Drugs, 10/08/09
Park IH et al. – Lovastatin can overcome gefitinib resistance, in NSCLC cells with K–Ras mutations, by down regulation of RAS protein, which leads to inhibition of both RAF/ERK and AKT pathways.
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Today in Basic Science/Genetics...keeping you current
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Multi-step binding of ADAMTS-13 to von Willebrand factor
Journal of Thrombosis and Haemostasis, 12/02/09
Combined genetic effect of CDK7 and ESR1 polymorphisms on breast cancer
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Today in Lung/Thoracic Oncology...keeping you current
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The Role of EGFR Inhibition in the Treatment of Non-Small Cell Lung Cancer
The Oncologist, 12/02/09
Prognostic Factors for Resected Non-Small Cell Lung Cancer with pN2 Status: Implications for Use of Postoperative Radiotherapy
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Today in Pharmacology/Therapy...keeping you current
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ETAR antagonist ZD4054 exhibits additive effects with aromatase inhibitors and fulvestrant in breast cancer therapy, and improves in vivo efficacy of anastrozole
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