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Absence of Granzyme B positive tumour-infiltrating lymphocytes in primary melanoma excisional biopsies is strongly associated with the presence of sentinel lymph node metastasis
Cellular Oncology, 09/23/09
van Houdt IS et al. – Sentinel Lymph Node (SLN) status is strongly related to clinical outcome in melanoma patients. These data support a role for cytotoxic T cells in the prevention of early metastasis of melanoma to the draining lymph nodes.
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