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Chao CI et al. – Neither red wine nor total alcohol consumption were associated with prostate cancer risk in this population of moderate drinkers.

Methods

We investigated the effect of red wine intake on the risk of prostate cancer using data prospectively collected in the California Men's Health Study (CMHS); CMHS is a multiethnic cohort of 84,170 men aged 45-69 years who were members of the Kaiser Permanente Southern and Northern California Health Plans
Information on demographic and lifestyle factors was collected using mailed questionnaires between 2002 and 2003

Results

A total of 1,340 incident prostate cancer cases identified from Surveillance, Epidemiology and End Result-affiliated cancer registries were included in the analyses
We did not find a clear association between red wine intake and risk of prostate cancer
Hazard ratio (HR) estimates for consuming <1 drink/week, 1 drink/week but <1 drink/day and 1 drink/day were 0.89, 95% confidence interval (0.74-1.07), 0.99 (0.83-1.17) and 0.88 (0.70-1.12), respectively
The lack of association for red wine intake was consistently observed when we restricted the analyses to those with and without a history of PSA screening
In addition, we also did not observe any association with prostate cancer for beer, white wine, liquor or combined alcoholic beverage intake (HR for combined alcoholic beverage intake of 5 drinks/day = 1.16 (0.83-1.63)

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