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Kamper–Jorgensen M et al. – Various blood safety initiatives have ensured a historically low risk of infection transmission through blood transfusion. Although further prevention of infection transmission is possible through, for example, nucleic acid testing and future introduction of pathogen inactivation, such initiatives are very costly in relation to the benefit they offer. Despite considerable costs, previous cost–effectiveness studies may have underestimated the costs per QALY gained by as much as 44%.

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