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See Latest ArticlesSurrogate end points for overall survival and local control in neoadjuvant rectal cancer trials: statistical evaluation based on the FFCD 9203 trial
Annals of Oncology, 09/18/09
Methy N et al. – Pathological parameters were not surrogate for OS or LC.
Methods- 742 eligible patients were randomly assigned to receive preoperative radiotherapy with or without concurrent chemotherapy
- Data analyses did not provide interpretable PTE measures for OS
- The highest PTE was reached by TRG, which explained 12% of the effect on local recurrence
- PTE explained by the CRM status was associated with a wide uncertainty (95% CI –81% to 105%), which does not exclude a potentially high degree of surrogacy
Today in Colorectal Cancer/Polyps...keeping you current
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Knockdown of peroxisome proliferator-activated receptor-beta induces less differentiation and enhances cell–fibronectin adhesion of colon cancer cells
Oncogene, 11/25/09
A blood-based biomarker panel for stratifying current risk for colorectal cancer
International Journal of Cancer, 11/25/09
iNOS activity is necessary for the cytotoxic and immunogenic effects of doxorubicin in human colon cancer cells
Molecular Cancer, 11/24/09
Today in GI Oncology...keeping you current
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A new staging system is more discriminant than conventional staging systems for unresectable hepatocellular carcinoma
Journal of Cancer Research & Clinical Oncology, 11/24/09
Pancreatic endocrine tumors: Expression profiling evidences a role for AKT-mTOR pathway
Journal of Clinical Oncology, 11/24/09
XPD codon 312 and 751 polymorphisms, and AFB1 exposure, and hepatocellular carcinoma risk
BMC Cancer, 11/20/09
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