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Optimizing the CD34 + cell dose for reduced-intensity allogeneic hematopoietic stem cell transplantation
Leukemia and Lymphoma, 09/18/09
Mehta J et al. – Low CD34 + cell doses increase allograft–related mortality and very high doses increase the risk of graft–versus–host disease. The optimum CD34 + cell dose remains undefined. The number of CD34 + cells infused, a potentially modifiable factor, affects survival after reduced–intensity allogeneic transplantation.
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