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Pomalidomide and Lenalidomide Induce p21WAF-1 Expression in Both Lymphoma and Multiple Myeloma through a LSD1-Mediated Epigenetic Mechanism
Cancer Research, 09/18/09
Escoubet–Lozach L et al. – The results provide new insights on the mechanism of action of pomalidomide and lenalidomide in the regulation of gene transcription, imply possible efficacy in p53 mutated and deleted cancer, and suggest new potential clinical uses as an epigenetic therapy.
Today in Basic Science/Genetics...keeping you current
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Survival analysis of cancer risk reduction strategies for BRCA1/2 mutation carriers
Journal of Clinical Oncology, 12/10/09
Prognosis of women with metastatic breast cancer by HER2 status and trastuzumab treatment: An institutional-based review
Journal of Clinical Oncology, 12/10/09
Association of BRCA1 mutations with occult primary ovarian insufficiency: A possible explanation for the link between infertility and breast/ovarian cancer risks
Journal of Clinical Oncology, 12/10/09
Today in Leukemia/Lymphoma...keeping you current
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Association of Oxidative Stress with Realgar-Induced Differentiation in Human Leukemia HL-60 Cells
Chemotherapy, 12/10/09
Rapid and reliable confirmation of acute promyelocytic leukemia by immunofluorescence staining with an antipromyelocytic leukemia antibody
Cancer, 12/10/09
Persistent altered fusion transcript splicing identifies RUNX1-RUNX1T1+ AML patients likely to relapse
European Journal of Haematology, 12/10/09
Today in Myeloproliferative Dz...keeping you current
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Genetic polymorphisms associated with outcome in multiple myeloma patients receiving high-dose melphalan
Bone Marrow Transplantation, 12/10/09
Inhibitory effect of baicalein on IL-6-mediated signaling cascades in human myeloma cells
European Journal of Haematology, 12/10/09
Age and platelet count are IPSS-independent prognostic factors in young patients with primary myelofibrosis and complement IPSS in predicting very long or very short survival
European Journal of Haematology, 12/10/09
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