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Role of Cyclic AMP Response Element–Binding Protein in Insulin-like Growth Factor-I Receptor Up-regulation by Sex Steroids in Prostate Cancer Cells
Cancer Research, 09/18/09
Genua M et al. – Insulin–like growth factor–I receptor (IGF–IR) overexpression may play a role in prostate cancer progression. The authors describe a novel mechanism of IGF–IR up–regulation and promoter activity by CREB activation, induced by sex steroids, through a nongenotropic signaling.
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Today in Basic Science/Genetics...keeping you current
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Activating Peroxisome Proliferator-Activated Receptor gamma Mutant Promotes Tumor Growth In vivo by Enhancing Angiogenesis
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Extracellular Signal–Regulated Kinase Signaling Pathway Regulates Breast Cancer Cell Migration by Maintaining slug Expression
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Today in Renal/Urologic...keeping you current
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Any proportion of ductal adenocarcinoma in radical prostatectomy specimens predicts extraprostatic extension
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Papillary renal cell carcinoma with diffuse clear cells and thyroid-like macrofollicular areas
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