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See Latest ArticlesPU.1 induces apoptosis in myeloma cells through direct transactivation of TRAIL
Oncogene, 09/21/09
Ueno S et al. – Upregulation of PU.1–induced transactivation of the TRAIL promoter in reporter assays, and disruption of the PU.1–binding site in the TRAIL promoter eliminated this transactivation. Therefore, the authors conclude that PU.1 is capable of inducing apoptosis in certain myeloma cells by direct transactivation of TRAIL.
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Today in Basic Science/Genetics...keeping you current
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Impact of additional chromosomal aberrations and BCR-ABL kinase domain mutations on the response to nilotinib in Philadelphia chromosome-positive chronic myeloid leukemia
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Today in Myeloproliferative Dz...keeping you current
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