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Expression of matrix metalloproteinase-9 and significance of a macrophage assay in eosinophilic granuloma
Annals of Diagnostic Pathology, 09/15/09
Zyada MM – There is a highly significant relationship between the expression of MMP–9 and macrophage count in EGs (P < .001), with recurrent lesions showing a higher mean expression of both MMP–9 and CD–68. There may be a cooperation between macrophages and MMP–9 in EGs, which correlates well with local recurrence. Their expression may therefore provide some prognostic indication of the possible aggressive and recurrence behavior of this lesion.
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