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See Latest ArticlesVitamin D Related Genes, CYP24A1 and CYP27B1, and Colon Cancer Risk
Cancer Epidemiology, Biomarkers & Prevention, 09/14/09
Dong LM et al. – Genetic association studies investigating the role of vitamin D in colon cancer have primarily focused on the vitamin D receptor (VDR), with limited data available for other genes in the vitamin D pathway, including vitamin D activating enzyme 1–alpha hydroxylase (CYP27B1) and vitamin D deactivating enzyme 24–alpha hydroxylase (CYP24A1). A possible interaction between CYP27B1 and UV–weighted sun exposure with proximal colon cancer was observed. As this is the first study to evaluate these genes in relation to colon cancer, additional studies are needed to confirm these results.
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Today in Basic Science/Genetics...keeping you current
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Today in Colorectal Cancer/Polyps...keeping you current
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Polymorphisms in the transforming growth factor beta 1 pathway in relation to colorectal cancer progression
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