Oncology Medical News about MET Mutations

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1. Report Shows Shift in Starting Salaries for Physicians

2. Recommendations on the use of 18F-FDG PET in oncology

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4. Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer

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Ethnic Differences and Functional Analysis of MET Mutations in Lung Cancer
Clinical Cancer Research, 09/15/09

Krishnaswamy S et al. – MET in lung cancer tissues contained nonsynonymous mutations in the semaphorin and juxtamembrane domains but not in the tyrosine kinase domain. All the MET mutations were germline. East Asians, African–Americans, and Caucasians had different MET genotypes and haplotypes. MET mutations in the semaphorin domain affected ligand binding.

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Prognostic significance of alterations in KRAS isoforms KRAS-4A/4B and KRAS mutations in colorectal carcinoma
The Journal of Pathology, 10/16/09 Relevance Score: 48%

Genetic Testing for Long-QT Syndrome. Distinguishing Pathogenic Mutations From Benign Variants
Circulation, 10/23/09 Relevance Score: 47%

Contralateral breast cancer risk in BRCA1 and BRCA2 mutation carriers
Journal of Clinical Oncology, 10/29/09 Relevance Score: 46%

MEFV mutations in Egyptian patients suffering from familial Mediterranean fever: analysis of 12 gene mutations
Rheumatology International, 10/16/09 Relevance Score: 46%

Vitamin D receptor expression is associated with PIK3CA and KRAS mutations in colorectal cancer
Cancer Epidemiology, Biomarkers & Prevention, 10/05/09 Relevance Score: 46%