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TGFBIp/betaig-h3 activates platelets and promotes thrombogenesis
Blood, 09/18/09
Kim H–J et al. – TGFBIp/betaig–h3 is a 68 kDa extracellular matrix protein that is functionally associated with the adhesion, migration, proliferation, and differentiation of various cells. The presence of TGFBIp in platelets led us to study the role of this protein in the regulation of platelet functions. The findings will increase the understanding of the novel mechanism of platelet activation, contributing to a better understanding of thrombotic pathways and the development of new antithrombotic therapies.
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