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Methylation status of normal background mucosa is correlated with occurrence and development of neoplasia in the distal colon
Human Pathology, 09/16/09
Hiraoka S et al. – The methylation of MYOD1 in the normal mucosa was significantly correlated with K–ras mutation in neoplastic tissue arising from the mucosa. Specific epigenetic changes in normal colonic mucosa may be correlated with the occurrence and development of neoplasia in the distal colon.
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