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Blackburn JS et al. – This study demonstrates that both the type I collagenase and PAR–1 activating functions of MMP–1 are required for melanoma progression, and suggests that MMP–1 may be a major contributor to the transformation of melanoma from non–invasive to malignant disease.

Today in Basic Science/Genetics...keeping you current

Melanoma-associated fibroblasts modulate NK cell phenotype and antitumor cytotoxicity
Proceedings of the National Academy of Sciences of the United States of America, 12/09/09

A gene expression signature that predicts the therapeutic response of the basal-like breast cancer to neoadjuvant chemotherapy
Breast Cancer Research and Treatment, 12/09/09

Expression of Hiwi in human esophageal squamous cell carcinoma is significantly associated with poorer prognosis
BMC Cancer, 12/09/09

Today in Dermatologic Oncology...keeping you current

Melanoma-associated fibroblasts modulate NK cell phenotype and antitumor cytotoxicity
Proceedings of the National Academy of Sciences of the United States of America, 12/09/09

Phase II trial of temozolomide and sorafenib in advanced melanoma patients with or without brain metastases
Clinical Cancer Research, 12/09/09

Dynamic Gene Expression Analysis Links Melanocyte Growth Arrest with Nevogenesis
Cancer Research, 12/09/09


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