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See Latest ArticlesAmplification of the ABCB1 region accompanied by a short sequence of 200bp from chromosome 2 in lung cancer cells
Cancer Genetics and Cytogenetics, 09/11/09
Kitada K et al. – The results demonstrated that the translocation occurred at the step of 100 nmol/L treatment and the BFB cycle initiated in the step of 400 nmol/L–treatment. It is likely that the translocation, preceding amplification by several selection steps, activated ABCB1 gene expression. The diversity in amplification profiles between the two sublines was generated by the separately operating BFB cycles, after an initial break–and–fusion that probably occurred in a single cell.
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Today in Basic Science/Genetics...keeping you current
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Today in Lung/Thoracic Oncology...keeping you current
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Lung cancer susceptibility among atomic bomb survivors in relation to CA repeat number polymorphism of epidermal growth factor receptor gene and radiation dose
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