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Cytogenetic abnormalities in essential thrombocythemia at presentation and transformation
International Journal of Hematology, 09/15/09
Sever M et al. – Two patients (1.2%) with normal karyotypes at presentation transformed to myelodysplastic syndrome and acute myeloid leukemia, respectively. Both acquired complex cytogenetic changes at the time of transformation. There is no rationale for repeating cytogenetic tests in ET patients on follow up, unless blood cell count changes suggest possible transformation.
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