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See Latest ArticlesAssociation Between MGMT Promoter Hypermethylation and p53 Mutation in Glioblastoma
Cancer Investigation, 09/21/09
Shamsara J et al. – O6–methylguanine–DNA methyltransferase (MGMT) is a DNA repair enzyme that removes alkyl groups from the O6 position of guanine. MGMT is transcriptionally silenced by promoter hypermethylation in several human neoplasia. The results suggested that epigenetic inactivation of MGMT plays an important role in the survival of glioblastoma patients and this inactivated gene involved in p53 mutation.
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Today in Basic Science/Genetics...keeping you current
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Thrombopoietin in normal and neoplastic stem cell development
Best Practice & Research: Clinical Haematology , 12/07/09
Mechanisms of mutations in myeloproliferative neoplasms
Best Practice & Research: Clinical Haematology , 12/07/09
Ursodeoxycholic acid switches oxaliplatin-induced necrosis to apoptosis by inhibiting reactive oxygen species production and activating p53-caspase 8 pathway in HepG2 hepatocellular carcinoma
International Journal of Cancer, 12/07/09
Today in Neurologic Oncology...keeping you current
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Glioblastoma with signet-ring morphology: a case report and review of the literature
Human Pathology, 12/07/09
Rosette forming glioneuronal tumor pineal gland and tectum: An intraoperative diagnosis on smear preparation
Diagnostic Cytopathology, 12/07/09
The expression level of sphingosine-1-phosphate receptor type 1 is related to MIB-1 labeling index and predicts survival of glioblastoma patients
Journal of Neuro-Oncology, 12/07/09
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