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In vivo prostaglandin E2 treatment alters the bone marrow microenvironment and preferentially expands short-term hematopoietic stem cells
Blood, 09/17/09
Frisch BJ et al. – These novel effects of PGE2 could be exploited clinically to increase donor ST–HSCs, which are highly proliferative and could accelerate hematopoietic recovery after stem cell transplantation.
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Today in BMT/SCT...keeping you current
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Unpredictability of iv Busulfan pharmacokinetics in children undergoing hematopoietic stem cell transplant for advanced beta thalassemia: Limited toxicity with a dose adjustment policy
Biology of Blood and Marrow Transplantation, 12/09/09
High levels of B-cell activating factor during the peri-transplant period are associated with the reduced incidence of acute graft-versus-host disease following the myeloablative allogeneic stem cell transplantation
Biology of Blood and Marrow Transplantation, 12/09/09
Improved survival with inhibitory Killer Immunoglobulin Receptor (KIR) gene mismatches and KIR haplotype B donors after nonmyeloablative, HLA-haploidentical bone marrow transplantation
Biology of Blood and Marrow Transplantation, 12/09/09
Today in Pharmacology/Therapy...keeping you current
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Phase II trial of temozolomide and sorafenib in advanced melanoma patients with or without brain metastases
Clinical Cancer Research, 12/09/09
A gene expression signature that predicts the therapeutic response of the basal-like breast cancer to neoadjuvant chemotherapy
Breast Cancer Research and Treatment, 12/09/09
A randomized, placebo-controlled trial (NCIC CTG MAP1) examining the effects of letrozole on mammographic breast density and other end organs in postmenopausal women
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