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[11C]Choline Positron Emission Tomography in Estrogen Receptor–Positive Breast Cancer
Clinical Cancer Research, 09/08/09
Contractor KB et al. – Novel radiotracers could potentially allow the identification of clinically aggressive tumor phenotypes. As choline metabolism increases during malignant transformation and progression of human mammary epithelial cells, the authors examined the ability of [11C]choline (CHO) positron emission tomography imaging to detect clinically aggressive phenotype in patients with estrogen receptor (ER)–positive breast cancer in vivo. CHO showed good uptake in most breast cancers and merits further investigation as a breast cancer imaging agent.
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Today in Breast...keeping you current
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Hepatocyte Nuclear Factor-4–Independent Synthesis of Coagulation Factor VII in Breast Cancer Cells and Its Inhibition by Targeting Selective Histone Acetyltransferases
Molecular Cancer Research, 12/11/09
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Today in Diagnostics/Radiology...keeping you current
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Immunoprofile of mesenchymal chondrosarcoma: aberrant desmin and EMA expression, retention of INI1, and negative estrogen receptor in 22 female-predominant central nervous system and musculoskeletal cases
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