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mTOR Is a Promising Therapeutic Target Both in Cisplatin-Sensitive and Cisplatin-Resistant Clear Cell Carcinoma of the Ovary
Clinical Cancer Research, 09/08/09
Mabuchi S et al. – mTOR is frequently activated in clear cell carcinoma and can be a promising therapeutic target in the management of clear cell carcinoma. Moreover, mTOR inhibition by RAD001 may be efficacious as a second–line treatment of recurrent disease in patients previously treated with cisplatin.
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Today in Basic Science/Genetics...keeping you current
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Knockdown of peroxisome proliferator-activated receptor-beta induces less differentiation and enhances cell–fibronectin adhesion of colon cancer cells
Oncogene, 11/25/09
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Embryoid body formation of human amniotic fluid stem cells depends on mTOR
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Today in Gynecologic Oncology...keeping you current
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Primary ex vivo cultures of human fallopian tube epithelium as a model for serous ovarian carcinogenesis
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