Oncology Medical News about Glioblastoma

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1. Report Shows Shift in Starting Salaries for Physicians

2. Recommendations on the use of 18F-FDG PET in oncology

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4. Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer

5. Sentinel node biopsy is important in mastectomy for ductal carcinoma in situ

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A Novel Splice Variant of GLI1 That Promotes Glioblastoma Cell Migration and Invasion
Cancer Research, 09/03/09

Lo H–W et al. – The family of GLI zinc finger transcription factors regulates the expression of genes involved in many important cellular processes, notably embryonal development and cellular differentiation. The glioma–associated oncogene homologue 1 (GLI1) isoform, in particular, has attracted much attention because of its frequent activation in many human cancers and its interactions with other signaling pathways, such as those mediated by K–RAS, transforming growth factor–beta, epidermal growth factor receptor, and protein kinase A.

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Distribution, cellular localization, and therapeutic potential of the tumor-associated antigen Ku70/80 in glioblastoma multiforme
Journal of Neuro-Oncology, 10/28/09 Relevance Score: 88%

Phase II Study of Neoadjuvant Imatinib in Glioblastoma: Evaluation of Clinical and Molecular Effects of the Treatment
Clinical Cancer Research, 10/01/09 Relevance Score: 88%

Multiple extracranial metastases from secondary glioblastoma multiforme: a case report and review of the literature
Journal of Neuro-Oncology, 11/18/09 Relevance Score: 87%

Antiglioma Immunological Memory in Response to Conditional Cytotoxic/Immune-Stimulatory Gene Therapy: Humoral and Cellular Immunity Lead to Tumor Regression
Clinical Cancer Research, 10/06/09 Relevance Score: 87%

Intratumoral concentrations of imatinib after oral administration in patients with glioblastoma multiforme
Journal of Neuro-Oncology, 10/01/09 Relevance Score: 87%