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(–)-Epigallocatechin gallate downregulates EGF receptor via phosphorylation at Ser1046/1047 by p38 MAPK in colon cancer cells
Carcinogenesis, 09/03/09
Adachi S et al. – The results strongly suggest that phosphorylation of EGFR at serine 1046/1047 via activation of p38 MAPK plays a pivotal role in EGCG–induced downregulation of EGFR in colon cancer cells.
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Today in Basic Science/Genetics...keeping you current
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Gene expression profiling identifies emerging oncogenic pathways operating in extranodal NK/T-cell lymphoma, nasal-type
Blood, 12/09/09
The sumoylation pathway is dysregulated in multiple myeloma and is associated with adverse patient outcome
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TCEAL7, a putative tumor suppressor gene, negatively regulates NF-kappaB pathway
Oncogene, 12/09/09
Today in Colorectal Cancer/Polyps...keeping you current
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Contribution of the 15 amino acid repeats of truncated APC to beta-catenin degradation and selection of APC mutations in colorectal tumours from FAP patients
Oncogene, 12/09/09
Impact of Two Supportive Care Interventions on Anxiety, Depression, Quality of Life, and Unmet Needs in Patients With Nonlocalized Breast and Colorectal Cancers
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