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Anti–von Willebrand factor aptamer ARC1779 for refractory thrombotic thrombocytopenic purpura
Transfusion, 09/11/09
Knobl P et al. – ARC1779 caused a clear and reproducible increase in PLT counts in an otherwise refractory TTP case. These clinical, pharmacokinetic, and pharmacodynamic data provide a rational basis for clinical trials with ARC1779 in TTP.
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