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The efficacy of individual-donation and minipool testing to detect low-level hepatitis B virus DNA in Taiwan
Transfusion, 09/04/09
Yang M–H et al. – Financial constraints are the main concern in implementing nucleic acid testing (NAT) as routine blood screening in Taiwan. The PROCLEIX ULTRIO assay (Ultrio) on the TIGRIS System (Novartis Diagnostics) was evaluated for its operational performance both for individual–donation testing (IDT) and in minipools of 4 (MP4) to develop a feasible solution. The higher yield rate for IDT versus MP4 demonstrates the benefit to implement a more sensitive NAT strategy in regions having significant OBI carriers such as Taiwan.
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