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Characterization of the bone marrow immunofluorescence test in childhood autoimmune neutropenia
International Journal of Laboratory Hematology, 09/09/09

Lane SW et al. – The bone marrow immunofluorescenece test (BMIFT) demonstrates autoantibodies to granulocytes and their precursors on fresh–frozen bone marrow slides. It may be used to differentiate childhood autoimmune neutropenia (AIN) from other causes of childhood neutropenia, even when circulating neutrophil counts are low. The BMIFT is a simple, highly specific test with excellent PPV and thus is a clinically useful test to confirm AIN in children.

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