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Familial gastric cancer and Li–Fraumeni syndrome
European Journal of Cancer Care, 09/11/09

Corso G et al. – Gastric cancer occurs in some familial diseases with inherited cancer predisposition. Genetic factors have been correlated with the hereditary diffuse gastric cancer and other familial gastric cancer conditions as hereditary non–polyposis colorectal cancer and Li–Fraumeni syndrome. The present study was aimed at searching for germ line mutations of TP53 gene in familial gastric cancer with cluster for Li–Fraumeni syndrome or Li–Fraumeni–like syndrome.

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