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See Latest ArticlesIncreased tryptophan degradation in patients with bronchus carcinoma
European Journal of Cancer Care, 09/08/09
Engin AB et al. – The authors conclude that in the majority of patients with non–small cell lung cancer and small cell lung cancer, enhanced tryptophan degradation can be observed. It seems to relate to an inflammatory response and may reflect activation of indoleamine (2,3)–dioxygenase at the tumour site. The capacity of the tumour to escape normal host immune defence may be influenced by tryptophan degradation. Results of this pilot study deserve further confirmation.
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