Oncology Medical News about thrombin generation

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Early thrombin generation and impaired fibrinolysis after SCT associate with acute GVHD
Bone Marrow Transplantation, 09/02/09

Pinomaki A et al. – Early maladaptation, that is, upregulated thrombin generation and inhibition of fibrinolysis, occurred in one–third of the SCT patients associating with the development of GVHD, a finding suggesting an interplay between coagulation and immunology during SCT.

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Thrombin generation assay as a possible tool for assessment of reduced activity of clotting factors induced by antiphospholipid antibodies and in-vitro evaluation of treatment options
Blood Coagulation & Fibrinolysis, 11/03/09 Relevance Score: 69%

Residual platelet factor V ensures thrombin generation in patients with severe congenital factor V deficiency and mild bleeding symptoms
Blood, 11/12/09 Relevance Score: 66%

Factor VIII contributes to platelet-fibrin thrombus formation via thrombin generation under low shear conditions
Thrombosis Research, 10/26/09 Relevance Score: 66%

A Randomized Clinical Trial Investigating the Relationship Between Aprotinin and Hypercoagulability in Off-Pump Coronary Surgery
Anesthesia & Analgesia, 10/21/09 Relevance Score: 65%

Involvement of human decidual cell-expressed tissue factor in uterine hemostasis and abruption
Thrombosis Research, 10/21/09 Relevance Score: 65%