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Absence of VOD in paediatric thalassemic HSCT recipients using defibrotide prophylaxis and intravenous Busulphan
British Journal of Haematology, 09/14/09
Cappelli B et al. – Oral defibrotide prophylaxis and i.v. busulphan safely abated VOD incidence in high–risk patients who had undergone HSCT. A galenic preparation of oral DF also permits this treatment in low–weight patients. Costs of DF prophylaxis are acceptable considering the reduced incidence of VOD.
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