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See Latest ArticlesTalampanel with standard radiation and temozolomide in patients with newly diagnosed glioblastoma: a multicenter phase II trial
Journal of Clinical Oncology, 09/02/09
Grossman SA et al. – Talampanel can be added to RT + TMZ without significant additional toxicity. The encouraging survival results in methylated and unmethylated patients suggest that blocking AMPA receotirs nat be a ysefyk strategy in newly diagnosed glioblastoma.
Methods- 72 patients with glioblastomas treated with talampanel + RT and TMZ
- Median f/u 18 mos
- 55 patients died
- Median survival time of 18.3 mos
- Talampanel was well-tolerated
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Today in Neurologic Oncology...keeping you current
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Prognostic Significance of Growth Kinetics in Newly Diagnosed Glioblastomas Revealed by Combining Serial Imaging with a Novel Biomathematical Model
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Recognition and Killing of Brain Tumor Stem-Like Initiating Cells by CD8+ Cytolytic T Cells
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Identification of membrane-type 1 matrix metalloproteinase tyrosine phosphorylation in association with neuroblastoma progression
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Today in Pharmacology/Therapy...keeping you current
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Effects of functional electrical stimulation on dysphagia caused by radiation therapy in patients with nasopharyngeal carcinoma
Supportive Care in Cancer, 12/08/09
Is there a role for intensifying induction therapy in acute myeloid leukaemia (AML)?
Best Practice & Research: Clinical Haematology , 12/08/09
Tailoring iron chelation by iron intake and serum ferritin: prospective EPIC study of deferasirox in 1744 patients with transfusion-dependent anemias
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